We learn more about COVID-19 each day. When public health experts learn something new, they sometimes need to change their recommendations to keep us all safe. This page puts all that advice in one place so you can easily find the most up to date COVID-19 guidelines for the United States.

TreatmentWhoWhenHow
Nirmatrelvir with Ritonavir (Paxlovid)Adults; children ages 12 years and olderStart as soon as possible; must begin within 5 days of when symptoms startTaken at home by mouth (orally)
Remdesivir (Veklury)Adults and childrenStart as soon as possible; must begin within 7 days of when symptoms startIntravenous (IV) infusions at a healthcare facility for 3 consecutive days
Molnupiravir (Lagevrio)AdultsStart as soon as possible; must begin within 5 days of when symptoms startTaken at home by mouth (orally)

Check with your healthcare provider or pharmacist if you are taking other medications to make sure the COVID-19 treatments can be safely taken at the same time.

How can I find treatments?

Talk to your healthcare provider and look online by using the Department of Health and Human Services’ “Test to Treat Locator.”

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  • Stay up to date with COVID-19 vaccines
  • Get tested if you have symptoms
  • Wear a mask around others for 10 days if you are exposed to someone with COVID-19.
  • If you are at high risk for severe illness, talk to your healthcare provider about whether you need to wear a mask and take other precautions
  • Stay up to date with COVID-19 vaccines
  • Get tested if you have symptoms
  • Wear a mask around others for 10 days if you are exposed to someone with COVID-19.

People may choose to mask at any time. People with symptoms, a positive test, or exposure to someone with COVID-19 should wear a mask.

For Healthcare Facilities: COVID-19 Community Levels do not apply in healthcare settings, such as hospitals and nursing homes. Instead, healthcare settings should continue to use community transmission rates and follow CDC’s infection prevention and control recommendations for healthcare workers.

If you are immunocompromised or high risk for severe disease, learn more about how to protect yourself with additional CDC recommendations for each COVID-19 Community Level.